Related Experiment Video
Updated: Jan 18, 2026

05:45
Validating Whole Genome Nanopore Sequencing, using Usutu Virus as an Example
Published on: March 11, 2020
9.3K
CLAE: A High-Fidelity Nanopore Sequencing Strategy for Read-Level Viral Variant Detection and Environmental RNA Virus
Hannah Yu1,2,3, Sarah Golconda1,2,3, Ga-Eun Lee1,2,3,4
1Center for Retrovirus Research, The Ohio State University, Columbus, OH, 43210, USA.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|September 11, 2025
Abstract:
High-fidelity (HF) long-read sequencing enables accurate profiling of microorganisms and pathogens at single-molecule resolution. However, current Oxford Nanopore Technologies (ONT)-a revolutionary platform offering real-time, portable sequencing at relatively low instrumental cost-suffer from severe read-length bias, limited accuracy (often

