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Prognostic discussions in patients with advanced lymphoma: Characteristics and challenges
Meghan McDarby1, Jaime Gilliland1, Rinchen Dolma1
1Department of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Palliative & Supportive Care
|September 12, 2025
Summary
Early prognostic discussions for advanced lymphoma patients focus on cure, often delaying comprehensive information. Oncologists balance hope with realism, needing strategies for clear communication amid diagnostic uncertainty.
Area of Science:
- Oncology
- Medical Communication
- Patient-Centered Care
Background:
- Prognostic discussions are vital for advanced lymphoma patients due to disease complexity and evolving treatments.
- Limited research exists on patient and clinician perspectives in early prognostic conversations for advanced lymphoma.
Purpose of the Study:
- To identify key experiences that can improve clinician communication and patient understanding of prognosis in advanced lymphoma.
- To explore patient and oncologist viewpoints on early prognostic discussions.
Main Methods:
- Qualitative study involving 19 patients with advanced lymphoma and 3 oncologists.
- Semi-structured interviews analyzed using thematic content analysis with consensus coding.
Main Results:
- Patients' early prognostic conversations primarily emphasized curative intent.
- Oncologists delayed deeper prognostic discussions due to incomplete data and patient concerns, balancing hope with information.
Conclusions:
- Communication strategies are needed to balance hope and realism in early advanced lymphoma prognostic discussions.
- Oncologists require guidance for managing information delivery, especially with diagnostic ambiguity.
- Future research should focus on inclusive sampling and optimizing the timing and content of prognostic discussions.
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