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Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
09:22

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Published on: November 4, 2015

[Echocardiographic and endomyocardial biopsy findings of right-sided hypertrophic obstructive cardiomyopathy]

M Fukuhara, O Koyama, F Hinami

    Journal of Cardiography
    |June 1, 1985
    PubMed

    Insights

    Hypertrophic cardiomyopathy (HCM) with right-sided obstruction shows distinct septal protrusions on cross-sectional echocardiograms. Histology reveals more significant fibrosis and myocardial disarray in obstructive HCM cases.

    Area of Science:

    • Cardiology
    • Pathology

    Context:

    • Hypertrophic cardiomyopathy (HCM) is a complex cardiac condition.
    • Right-sided obstruction presents a specific challenge in HCM diagnosis and management.

    Purpose:

    • To differentiate hypertrophic cardiomyopathy (HCM) with right-sided obstruction from HCM without obstruction using echocardiography and histology.
    • To identify characteristic echocardiographic and histopathological features associated with right-sided obstructive HCM.

    Summary:

    • Echocardiographic and histological studies compared four patients with obstructive HCM and five without.
    • Cross-sectional echocardiography, particularly short-axis views, identified rightward septal protrusions in obstructive HCM.
    • Histological analysis of right ventricular septal biopsies showed more interstitial fibrosis and myocardial fiber disarray in obstructive HCM.

    Impact:

    • Cross-sectional echocardiography is a reliable tool for detecting right-sided obstruction in HCM.
    • Histopathological findings correlate with the presence and severity of right-sided obstruction in HCM.
    • Improved diagnostic accuracy for obstructive HCM can lead to better patient management.

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