Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Design Example: Sustainability in Concrete Building01:26

Design Example: Sustainability in Concrete Building

390
As the construction industry moves towards more eco-friendly practices, concrete's adaptability and its ability to incorporate sustainable features make it a key material in the drive towards greener building solutions.
There are multiple approaches to achieve sustainability in a commercial concrete building. For instance, construct a concrete parking area under the building, utilizing pervious concrete paver blocks in open areas to facilitate rainwater collection through an underground...
390
Design Example: Alignment of a Road Line Using GIS01:17

Design Example: Alignment of a Road Line Using GIS

337
The alignment of a road line using Geographic Information Systems (GIS) is a critical process in civil engineering, combining advanced technology with practical decision-making. This methodology begins with the collection of geospatial data, including information on land cover, geomorphology, drainage patterns, slope, and contour details. Such data is typically acquired through satellite imagery and GIS tools, offering a comprehensive understanding of the terrain.Once the data is gathered, it...
337
Prismatic Beams: Problem Solving01:15

Prismatic Beams: Problem Solving

441
In the design of a supported timber beam subjected to a distributed load, both the beam's physical dimensions and the timber's characteristics, such as its grade and species, are critical. These factors determine the allowable stress values, which are crucial for calculating the necessary beam depth to ensure structural integrity and safety.
The design begins with analyzing the beam as a free body to identify moments and force balances, thereby determining support reactions. Next, the...
441
Design of Prismatic Beams for Bending01:23

Design of Prismatic Beams for Bending

613
The design of prismatic beams, structural elements with a uniform cross-section, focuses on ensuring safety and structural integrity under load. The design process begins by determining the allowable stress, either from material properties tables, or by dividing the material's ultimate strength by a safety factor. This safety factor is essential for accommodating uncertainties, and varies depending on the material—timber, steel, or concrete—with each having unique strength and...
613
Design Consideration01:22

Design Consideration

550
Designing a structure involves a series of considerations, primarily the material's ultimate strength, calculated through tests that measure changes under increased force until the material reaches its breaking point or limit. The ultimate load, where the material breaks, is divided by its original cross-sectional area, resulting in the ultimate normal stress or strength. The ultimate shearing stress is another significant factor taken into account.
The factor of safety is another key...
550
Design Example: Deciding Thickness of Lubricating Fluid in a Shaft01:23

Design Example: Deciding Thickness of Lubricating Fluid in a Shaft

332
Effective lubrication between a rotating shaft and its bearing housing is essential in rotating machinery to minimize friction, wear, and energy loss. With carefully controlled thickness and viscosity, the lubricant layer prevents metal-to-metal contact, ensuring smooth operation.
To calculate the required thickness of the lubricant layer, the tangential velocity at the shaft's surface must first be determined. This velocity is calculated by converting the rotational speed to angular velocity...
332

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Merging Micellar Catalysis and C-H Activation: Silver-Free Direct Arylation of Fluoroarenes in Water.

ChemSusChem·2026
Same author

Accessing Long-Lived, Highly Stable Phosphine-Ligand-Free Palladium Hydrides via Palladium-Micelle Synergy.

Journal of the American Chemical Society·2026
Same author

Sustainable and Scalable Redesign of PS-750-M Synthesis While Retaining Micellar Catalytic Efficiency.

ACS sustainable chemistry & engineering·2026
Same author

Engineered aldehyde dehydrogenases for amide bond formation.

Science (New York, N.Y.)·2026
Same author

Solvent Sustainability in Drug Discovery: Where Are We Now, and How Can We Improve?

Journal of medicinal chemistry·2025
Same author

Editorial.

Chimia·2025

Related Experiment Video

Updated: Jan 18, 2026

Solvent Bonding for Fabrication of PMMA and COP Microfluidic Devices
04:54

Solvent Bonding for Fabrication of PMMA and COP Microfluidic Devices

Published on: January 17, 2017

17.1K

Solvent Selection for Circular Designs - Bridging Process Needs and Sustainability Goals.

Michael U Luescher1, Alessia Valotta2, Julien Haber1

  • 1Chemical & Analytical Development, Novartis Pharma AG, CH-4056 Basel, Switzerland.. michael-1.luescher@novartis.com.

Chimia
|September 12, 2025
PubMed
Summary
This summary is machine-generated.

The pharmaceutical industry can improve sustainability by adopting circular economy principles, focusing on efficient solvent selection to minimize waste and resource consumption in active pharmaceutical ingredient (API) manufacturing.

Keywords:
Circular economyDistallationLCASolvent selectionSustainable process development

More Related Videos

Designed for Molecular Recycling: A Lignin-Derived Semi-aromatic Biobased Polymer
10:22

Designed for Molecular Recycling: A Lignin-Derived Semi-aromatic Biobased Polymer

Published on: November 30, 2020

3.9K
Structural Design and Manufacturing of a Cruiser Class Solar Vehicle
14:57

Structural Design and Manufacturing of a Cruiser Class Solar Vehicle

Published on: January 30, 2019

14.4K

Related Experiment Videos

Last Updated: Jan 18, 2026

Solvent Bonding for Fabrication of PMMA and COP Microfluidic Devices
04:54

Solvent Bonding for Fabrication of PMMA and COP Microfluidic Devices

Published on: January 17, 2017

17.1K
Designed for Molecular Recycling: A Lignin-Derived Semi-aromatic Biobased Polymer
10:22

Designed for Molecular Recycling: A Lignin-Derived Semi-aromatic Biobased Polymer

Published on: November 30, 2020

3.9K
Structural Design and Manufacturing of a Cruiser Class Solar Vehicle
14:57

Structural Design and Manufacturing of a Cruiser Class Solar Vehicle

Published on: January 30, 2019

14.4K

Area of Science:

  • Pharmaceutical Manufacturing
  • Environmental Science
  • Green Chemistry

Background:

  • The pharmaceutical sector faces environmental challenges, including significant waste generation and resource depletion from raw material extraction and active pharmaceutical ingredient (API) manufacturing.
  • Linear economic models contribute to these environmental issues, necessitating a shift towards sustainable practices.
  • Solvent usage represents a major component of input mass and waste in pharmaceutical processes, highlighting it as a critical area for improvement.

Purpose of the Study:

  • To examine the application of circular economy principles to solvent selection in pharmaceutical process design.
  • To highlight the importance of solvent choice as a key factor in achieving sustainable pharmaceutical development.
  • To explore how resource efficiency and waste minimization can be integrated into pharmaceutical operations.

Main Methods:

  • Review of circular economy principles relevant to chemical process design.
  • Analysis of solvent usage in pharmaceutical manufacturing.
  • Case study or theoretical examination of circular solvent selection strategies.

Main Results:

  • Circular economy principles offer a viable framework for enhancing sustainability in pharmaceutical operations.
  • Strategic solvent selection, guided by circular economy tenets, can significantly reduce waste and resource consumption.
  • Integrating circularity into solvent choice is crucial for sustainable pharmaceutical development.

Conclusions:

  • Adopting circular economy principles, particularly in solvent selection, is essential for a more sustainable pharmaceutical industry.
  • This approach benefits both environmental health and community well-being.
  • Sustainable solvent strategies are central to the future of pharmaceutical process design.