Effect of vitamin D on postoperative atrial fibrillation in patients undergoing coronary artery bypass grafting: a systematic review and meta-analysis
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View abstract on PubMed
Summary
This summary is machine-generated.Vitamin D supplementation significantly reduces the incidence of postoperative atrial fibrillation (POAF) in patients undergoing coronary artery bypass grafting (CABG). This meta-analysis found no significant impact on hospital stay duration.
Area Of Science
- Cardiology
- Endocrinology
- Clinical Trials
Background
- Postoperative atrial fibrillation (POAF) is a common complication following coronary artery bypass grafting (CABG).
- Vitamin D's anti-inflammatory and cardioprotective properties suggest a potential role in preventing POAF.
Purpose Of The Study
- To evaluate the efficacy of vitamin D supplementation in reducing the incidence of POAF in patients undergoing CABG.
Main Methods
- A systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted.
- Searches were performed in PubMed and Cochrane Central Register of Controlled Trials up to May 2023.
- Four RCTs involving 694 patients were included in the final analysis.
Main Results
- Vitamin D supplementation significantly decreased the incidence of POAF in CABG patients (RR: 0.55; P=0.0003).
- No significant reduction in hospital length of stay was observed with vitamin D administration (WMD: -0.14; P=0.68).
- The heterogeneity among studies for POAF incidence was low (I²=1%).
Conclusions
- Vitamin D supplementation is effective in reducing POAF incidence in CABG patients.
- Further large-scale studies are warranted to investigate diverse populations and broader outcomes.
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