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Updated: Jan 18, 2026

Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
Extraphyseal Anterior Cruciate Ligament Reconstruction and Lateral Tenodesis Using Hamstrings for Prepubescent
Alberto Grassi1,2, Stefano Zaffagnini1,2, Kyle Borque3
1From II Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Abstract:
Anterior cruciate ligament injuries in prepubescent skeletally immature patients with significant remaining growth pose a serious challenge as surgeons must balance the desire to restore stability to the knee and prevent meniscal and chondral damage with the risk of iatrogenic injury to the open tibial and femoral physes. A physeal-sparing intra- and extra-articular reconstruction, which is a modification of a long-used "over-the-top and lateral extra-articular tenodesis" technique, is proposed as a safe approach to treat these patients. This article reports on the surgical details of this technique.

