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Updated: Jan 18, 2026

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings
Published on: March 30, 2014
Exploring resource availability for nurses implementing HIV prevention guidelines in primary healthcare facilities.
Junior M Ntimani1, Andile G Mokoena-de Beer1, Deliwe R Phetlhu1
1Nursing Sciences Department, School of Health Sciences, Sefako Makgatho Health Sciences University, Pretoria, South Africa.
Resource limitations in South African public health facilities impede pre-exposure prophylaxis (PrEP) uptake. Strengthening infrastructure, human resources, and data systems is crucial for effective HIV prevention.
Area of Science:
- Public Health
- HIV Prevention
- Healthcare Resource Management
Background:
- Pre-exposure prophylaxis (PrEP) is effective in reducing new HIV infections.
- Resource limitations in South African public health facilities hinder PrEP uptake despite established guidelines.
- Nurses face challenges implementing PrEP due to inadequate resources.
Purpose of the Study:
- To explore resource availability for nurses implementing PrEP guidelines in Johannesburg primary health settings.
- To identify barriers and facilitators to PrEP implementation related to resource availability.
- To assess the impact of structural and systemic factors on PrEP guideline implementation.
Main Methods:
- Qualitative exploratory design with an interpretive approach.
- Study conducted in four primary healthcare facilities in Johannesburg, South Africa.
- Semi-structured interviews with 19 nurses, analyzed using thematic analysis.
- Donabedian's framework used to assess structure, process, and outcomes.
Main Results:
- Three key themes emerged: structural inadequacies, insufficient healthcare system support, and unclear performance tracking.
- Resource limitations significantly impact the effective implementation of PrEP guidelines.
- Both barriers and facilitators influence PrEP implementation, emphasizing the need for healthcare system strengthening.
Conclusions:
- Critical resource limitations, including infrastructure and human resources, hinder PrEP implementation.
- Robust data management systems are essential for successful PrEP programs.
- Policy interventions are needed to strengthen infrastructure and human resources to improve PrEP uptake and retention.
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