Respiratory Involvement During the Course of Hypocomplementemic Urticarial Vasculitis: A Case Report

Hypocomplementemic urticarial vasculitis syndrome is a rare small-vessel vasculitis characterized by the combination of vasculitis and chronic urticaria. The hypocomplementemic form is distinguished by a more severe clinical presentation than the normocomplementemic form, with prognosis influenced by respiratory involvement. Due to its rarity and the similarities in presentation to systemic lupus erythematosus (SLE), diagnosis may be delayed and treatment may be inappropriate. We report the case of a young non-smoking female patient with a history of SLE refractory to standard treatments, whose progression was marked by severe and irreversible obstructive ventilatory disorder. This case aims to highlight the potential for severe and irreversible obstructive disorders that may occur in this condition in young non-smoking patients.