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Updated: Jan 18, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
[Contribution of clinical pharmacists to medication reconciliation]
Natacha Pougnier1, Léonard Naïmi1, Stéphanie Delestras2
1Unité de soins aigüs, Service de médecine interne, Hôpital de La Tour, 1217 Meyrin/Genève.
Abstract:
A patient's hospital stay includes several transition points (admission, discharge, transfer), each of which can result in information gaps. Discrepancies between prior treatments and current prescriptions may then occur. In Switzerland, such errors account for a significant proportion of adverse drug reactions, which are responsible for 32,000 hospital admissions and 700 deaths per year. These errors could be avoided through high-quality medication reconciliation. In 2006, the WHO High 5s project introduced standardized protocols. Since then, involving clinical pharmacists has proven to improve reconciliation and offers opportunities to enhance the healthcare system.
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