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Prevalence and Predisposing Factors of Periapical Osteoperiostitis: A Retrospective Cross-Sectional Study
Marie Mora1, Jonathan Nguyen1, Siddarth Mehta1
1New York University, New York, New York, USA.
International Endodontic Journal
|September 12, 2025
Summary
Periapical osteoperiostitis (PO) prevalence was 29.3% in maxillary posterior teeth. Mucositis, lesion size, and sinus root distance significantly increase PO risk.
Area of Science:
- Dentistry
- Oral Radiology
- Endodontics
Background:
- Periapical osteoperiostitis (PO) is a periosteal reaction on the maxillary sinus floor.
- Radiographically, PO appears as a radiopaque halo around affected maxillary posterior tooth roots.
- Literature lacks data on PO prevalence and predisposing factors.
Purpose of the Study:
- Evaluate the prevalence of Periapical Osteoperiostitis (PO) in maxillary posterior teeth.
- Identify predisposing factors associated with PO development.
Main Methods:
- Cone-beam computed tomography (CBCT) scans from 335 patients were analyzed.
- Data collected included PO presence, mucositis, lesion size, and sinus-root distances.
- Statistical analysis involved chi-square, Fisher's tests, and logistic regression.
Main Results:
- Periapical osteoperiostitis (PO) was present in 29.3% of the evaluated CBCT scans.
- Mucositis increased PO odds by 3.37 times.
- Larger lesion size and greater vertical sinus-root distance were significantly associated with PO.
Conclusions:
- The prevalence of PO in this study was higher than previously reported.
- Mucositis, lesion size, and vertical sinus-root distance are significant risk factors for PO.
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