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Detection of optic disc abnormalities using retro-mode scanning laser ophthalmoscopy
Jianping Xiong1, Shiqi Xie1, Hongshuang Lu1
1Department of Ophthalmology and Visual Science, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 1138510, Japan.
Japanese Journal of Ophthalmology
|September 12, 2025
Summary
Retro-mode scanning laser ophthalmoscopy (RMSLO) effectively detects optic disc abnormalities in highly myopic eyes. This imaging technique identifies lamina cribrosa (LC) defects and enlarged pores, aiding in the diagnosis of myopia-related optic nerve damage.
Area of Science:
- Ophthalmology
- Medical Imaging
- Optic Nerve Research
Background:
- High myopia is associated with optic disc abnormalities.
- Accurate detection of these abnormalities is crucial for patient management.
- Existing imaging techniques may have limitations in visualizing subtle changes.
Purpose of the Study:
- To evaluate the efficacy of retro-mode scanning laser ophthalmoscopy (RMSLO) in detecting optic disc abnormalities in highly myopic eyes.
- To correlate RMSLO findings with optical coherence tomography (OCT) findings of the lamina cribrosa (LC).
Main Methods:
- Retrospective clinical study involving patients with high myopia.
- RMSLO and optic disc-centered OCT imaging were performed.
- Hyporeflective areas in RMSLO images were analyzed and compared with LC abnormalities identified by OCT.
Main Results:
- RMSLO detected hyporeflective areas on the optic nerve head in 97.4% of highly myopic eyes studied.
- These hyporeflective areas corresponded to lamina cribrosa (LC) defects and enlarged pores seen on OCT.
- The extent of LC abnormalities on OCT correlated with the width of hyporeflective areas on RMSLO.
Conclusions:
- RMSLO is a valuable tool for identifying optic disc abnormalities in high myopia.
- The technique can visualize hyporeflective areas indicative of LC defects and enlarged pores.
- RMSLO aids in the detection of lamina cribrosa abnormalities in the context of high myopia.
