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Inter-software agreement in abdominal computed diffusion-weighted imaging: apparent diffusion coefficient and image

Tsukasa Yoshida1, Atsushi Urikura2,3, Kazuaki Nakashima4

  • 1Department of Diagnostic Radiology, Shizuoka Cancer Center, Shizuoka, Japan. ts.yoshida@scchr.jp.

Abdominal Radiology (New York)
|September 12, 2025
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Summary
This summary is machine-generated.

Two software programs show strong agreement and high reliability for apparent diffusion coefficient (ADC) values in abdominal computed diffusion-weighted imaging (cDWI). Image quality differences are minimal, indicating consistent results for clinical use.

Keywords:
Apparent diffusion coefficientContrast-to-noise ratioDiffusion-weighted magnetic resonance imagingMagnetic resonance imagingSignal-to-noise ratio

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Area of Science:

  • Radiology
  • Medical Imaging
  • Diffusion-Weighted Imaging

Background:

  • Abdominal diffusion-weighted imaging (DWI) is crucial for diagnosing various conditions.
  • Computed DWI (cDWI) generation involves different software, necessitating validation of consistency.
  • Apparent diffusion coefficient (ADC) values are key quantitative metrics in DWI.

Purpose of the Study:

  • To evaluate the agreement in ADC values between two software programs for abdominal cDWI.
  • To assess and compare the image quality, including signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR), of cDWI generated by these software programs.

Main Methods:

  • Retrospective analysis of 154 patients undergoing abdominal DWI at 3.0T.
  • cDWI generated with b-values of 1500 and 2000 s/mm² using scanner console and commercial software.
  • ADC, SNR, and CNR measurements in normal tissues; Bland-Altman analysis and intraclass correlation coefficients (ICC) for agreement and reliability.

Main Results:

  • High agreement and reliability for ADC values between software (ICCs 0.991-1.000).
  • ADC bias and limits of agreement were minimal.
  • Significant differences in SNR and CNR were observed, but deemed clinically insignificant.

Conclusions:

  • ADC values derived from abdominal cDWI are highly consistent between the evaluated software programs.
  • Image quality metrics (SNR, CNR) show some differences, but these are unlikely to impact clinical interpretation.
  • The findings support the interchangeability of ADC values from both software programs for abdominal cDWI analysis.