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Application of single-layer continuous duct-to-mucosa pancreaticojejunostomy in oncologic pancreaticoduodenectomy

  • 0Pancreas Center, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China; Pancreas Institute, Nanjing Medical University, Nanjing, China.
Seminars in Oncology +

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September 12, 2025

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September 12, 2025

View abstract on PubMed

Summary

This summary is machine-generated.

Single-layer continuous duct-to-mucosa pancreaticojejunostomy is a safe and effective technique for preventing clinically relevant pancreatic fistula after pancreaticoduodenectomy. This straightforward method shows favorable outcomes and applicability across various pancreatic conditions.

Area Of Science

  • Gastroenterology
  • Surgical Oncology
  • Abdominal Surgery

Background

  • Pancreaticojejunostomy is crucial in pancreaticoduodenectomy.
  • Failure can lead to clinically relevant pancreatic fistula (CRPF), causing severe complications.

Purpose Of The Study

  • To evaluate the safety and feasibility of single-layer continuous duct-to-mucosa (SCD) pancreaticojejunostomy.
  • To assess its efficacy in preventing CRPF.

Main Methods

  • Prospective data collection of baseline and perioperative information.
  • Study included 156 patients undergoing SCD pancreaticojejunostomy from January to December 2020.

Main Results

  • Mean pancreaticojejunostomy time: 6.5 min; mean operation time: 247.6 min.
  • CRPF occurred in 19.9% of patients.
  • Severe complications (Clavien-Dindo ≥III) in 17.3%; mean hospitalization: 17.2 days; 90-day mortality: 0.0%.

Conclusions

  • SCD pancreaticojejunostomy is an efficient and straightforward technique.
  • It is applicable to diverse pancreatic conditions.
  • The method demonstrates favorable clinical outcomes in preventing CRPF.

Keywords: