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Updated: Jan 18, 2026

A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
Published on: August 8, 2020
Split-thickness skin graft using scalp as a donor site for third-degree burn treatment in a newborn (case report)
Paula Andrea Pérez Franco1, Sebastian Murcia Espino2, Mauricio Alfonso Uribe Rodríguez3
1Plastic Surgeon - Universidad Militar Nueva Granada, Colombia.
Introduction And Importance:
Neonatal burns are uncommon but represent a critical medical challenge due to the physiological vulnerability of newborns, including fragile skin, immature immune response, and limited physiological reserves. Most burns in this population are iatrogenic, often preventable with proper care and equipment handling. The absence of standardized protocols complicates management, making each case an opportunity to refine treatment strategies and highlight prevention.
Case Presentation:
We present a case of a 16-hour-old male newborn with a third-degree thermal contact burn to the right forearm caused by overheated saline bags. Initial treatment included autolytic debridement and temporary coverage with a cadaveric skin allograft. Definitive closure was achieved using a split-thickness autologous skin graft harvested from the scalp.
Clinical Discussion:
The use of a cadaveric skin allograft improved wound bed conditions, facilitating successful autologous grafting. The scalp donor site provided rapid healing, minimal scarring, and early hair regrowth. This case reinforces the importance of careful thermal control in clinical environments and demonstrates the efficacy of a staged surgical approach in neonatal patients.
Conclusion:
Scalp skin grafting is a reliable option in neonates, offering favorable healing and cosmetic outcomes. A two-stage grafting strategy can enhance graft success and minimize donor site morbidity.
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