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Pulmonary Hypertension Associated With Interstitial Lung Diseases.
Arun Jose1, Namita Sood2, Jean M Elwing1
1University of Cincinnati, Cincinnati, OH.
Chest
|September 12, 2025
Summary
Interstitial lung disease (ILD) with pulmonary hypertension (PH) presents complex diagnostic and management challenges. This case-based review offers practical strategies for diagnosing and treating ILD-associated PH (ILD-PH).
Area of Science:
- Pulmonology
- Cardiology
- Internal Medicine
Background:
- Interstitial lung disease (ILD) involves lung inflammation and fibrosis.
- Pulmonary hypertension (PH) commonly complicates fibrotic ILDs.
- ILD-associated PH (ILD-PH) management is complex due to comorbidities.
Purpose of the Study:
- To present a case-based discussion of ILD-PH.
- To address diagnostic and management challenges in ILD-PH.
- To provide a practical, evidence-based framework for ILD-PH diagnosis and treatment.
Main Methods:
- Longitudinal, case-based discussion format.
- Focus on diagnostic workup pearls and pitfalls.
- Emphasis on practical, evidence-based management strategies.
Main Results:
- Highlights complexities in diagnosing ILD-PH.
- Discusses challenges in disentangling comorbidity contributions to PH.
- Addresses limited evidence for PH-specific medications in ILD-PH.
Conclusions:
- Accurate diagnosis and management of ILD-PH require a structured approach.
- Case-based learning is valuable for complex ILD-PH cases.
- Further evidence is needed for PH-specific therapies in ILD-PH.
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