Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Serum Laboratory Studies, Stool Test, Breath Test01:30

Serum Laboratory Studies, Stool Test, Breath Test

768
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
768

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Inclusion of <i>Prosopis laevigata</i> Pods in Finishing Lamb Diets Affects Performance and Induces Non-Target Metabolomic Modifications in the Liver and Meat.

Animals : an open access journal from MDPI·2026
Same author

Portable Electronic Olfactometer for Non-Invasive Screening of Canine Ehrlichiosis: A Proof-of-Concept Study Using Machine Learning.

Veterinary sciences·2026
Same author

A Non-Invasive Diagnostic Platform for Canine Leishmaniasis Using VOC Analysis and Distributed Veterinary Infrastructure.

Veterinary sciences·2025
Same author

Impact of Calcium Propionate Supplementation on the Lactation Curve and Milk Metabolomic Analysis on Rambouillet Ewes.

Veterinary sciences·2025
Same author

Molecularly imprinted polymers (MIPs) as efficient catalytic tools for the oxidative degradation of 4-nonylphenol and its by-products.

Environmental science and pollution research international·2023
Same author

Molecularly imprinted polymers for environmental adsorption applications.

Environmental science and pollution research international·2022

Related Experiment Video

Updated: Jan 18, 2026

Fruit Volatile Analysis Using an Electronic Nose
11:02

Fruit Volatile Analysis Using an Electronic Nose

Published on: March 30, 2012

22.3K

Colorectal Cancer Detection Through Sweat Volatilome Using an Electronic Nose System and GC-MS Analysis.

Cristhian Manuel Durán Acevedo1, Jeniffer Katerine Carrillo Gómez1,2, Gustavo Adolfo Bautista Gómez1

  • 1Multisensory Systems and Pattern Recognition Research Group, Faculty of Engineering and Architecture, University of Pamplona (UP), Pamplona 543050, Colombia.

Cancers
|September 13, 2025
PubMed
Summary

An electronic nose (E-nose) and GC-MS analysis of sweat volatile organic compounds (VOCs) show promise for early colorectal cancer (CRC) detection. The E-nose achieved 97% accuracy, offering a reliable, non-invasive diagnostic tool.

Keywords:
GC-MSbiomarkerscolorectal cancerelectronic nosemachine learningmultivariate analysissweat

More Related Videos

Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry
08:23

Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry

Published on: March 9, 2018

9.3K
Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
07:35

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

7.3K

Related Experiment Videos

Last Updated: Jan 18, 2026

Fruit Volatile Analysis Using an Electronic Nose
11:02

Fruit Volatile Analysis Using an Electronic Nose

Published on: March 30, 2012

22.3K
Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry
08:23

Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry

Published on: March 9, 2018

9.3K
Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
07:35

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

7.3K

Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Oncology

Background:

  • Colorectal cancer (CRC) is a major global health concern, necessitating improved early detection methods.
  • Current diagnostic tools often lack non-invasiveness or accessibility.
  • Volatile organic compounds (VOCs) in sweat present a potential biomarker source for CRC.

Purpose of the Study:

  • To assess the efficacy of a microelectromechanical systems (MEMS)-based electronic nose (E-nose) combined with gas chromatography-mass spectrometry (GC-MS) for detecting CRC.
  • To analyze sweat VOCs for novel CRC diagnostic markers.

Main Methods:

  • Collected 136 sweat samples from 68 participants (CRC patients and healthy controls).
  • Utilized solid-phase microextraction (SPME) for sample preparation.
  • Analyzed samples using GC-MS and a 14-sensor MEMS E-nose system.
  • Applied multivariate statistics (PCA, PLS-DA) and machine learning (LDA, LR, SVM, k-NN) for data analysis.

Main Results:

  • GC-MS identified significant VOC differences between CRC patients and controls.
  • k-NN classifier achieved 81% accuracy with GC-MS data.
  • LDA classifier achieved 97% accuracy with E-nose data for CRC detection.

Conclusions:

  • Sweat volatilome analysis, using E-nose and GC-MS, is a promising non-invasive approach for early CRC detection.
  • Advanced data processing enhances the reliability of this diagnostic strategy.
  • This complementary approach offers a potential breakthrough in accessible cancer diagnostics.