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Postoperative Acute Pancreatitis After Pancreatic Resections-A Narrative Review and a Diagnostic Algorithm.
Ewa Grudzińska1, Magdalena Gajda1
1Department of Gastrointestinal Surgery, Medical University of Silesia, 40-752 Katowice, Poland.
Cancers
|September 13, 2025
Summary
Postoperative acute pancreatitis (POAP) is a dangerous complication after pancreatic surgery, often linked to pancreatic fistulas. This review summarizes POAP diagnostics, prevention, and treatment, proposing an early detection algorithm.
Area of Science:
- Gastroenterology and Hepatology
- Surgical Oncology
- Clinical Research
Background:
- Pancreatic cancer surgery offers the only potential cure but carries significant risks.
- Postoperative pancreatic fistula (POPF) is a major complication, strongly associated with postoperative acute pancreatitis (POAP).
- POAP presents challenges due to a lack of standardized definitions and treatment protocols.
Purpose of the Study:
- To review current literature on postoperative acute pancreatitis (POAP).
- To summarize diagnostic, prophylactic, and therapeutic strategies for POAP.
- To propose an algorithm for early POAP detection.
Main Methods:
- Comprehensive literature search on POAP following pancreatic surgery.
- Analysis of diagnostic criteria, preventive measures, and treatment options.
- Development of a clinical algorithm based on existing evidence.
Main Results:
- POAP is a significant and dangerous complication following pancreatic surgery.
- Existing literature highlights a strong link between POPF and POAP.
- Current management lacks unified guidelines, hindering research and clinical practice.
Conclusions:
- POAP requires standardized definitions and treatment guidelines for improved patient outcomes.
- An early detection algorithm for POAP is proposed to aid clinical decision-making.
- Further research is essential to refine POAP management strategies.
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