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A Substance-Based Medical Device for Managing Hemorrhoidal Disease: Output from a Cross-Sectional Survey

Roberto Cioeta1, Paola Muti2,3, Marta Rigoni2,3

  • 1Aboca SpA, 52037 Sansepolcro, Italy.

Journal of Clinical Medicine
|September 13, 2025
PubMed

Background: Hemorrhoidal disease (HD) is a common anorectal condition characterized by symptoms such as bleeding, pain, discomfort and itching. While often underdiagnosed due to patient reluctance to seek care, HD significantly impacts quality of life (QoL). Conservative treatments are preferred for low-grade HD, with increasing interest in natural substance-based therapies. Materials and Methods: A large-scale survey was conducted using a digital platform to collect real-world data (RWD) from patients, pharmacists and physicians. The research assessed perceived effectiveness, safety, tolerability, quality of life (QoL) and usage patterns of NeoFitoroid BioOintment. Quantitative analysis was also performed using a global score (GS) based on Likert scale ratings and their distribution. Results: A total of 2618 participants were included. A strong concordance across the three participating cohorts in the answers provided for all items of the questionnaire was observed. The descriptive analysis revealed high grades of effectiveness, safety and tolerability. Indeed, over 90% of respondents rated the product as "good" or "excellent" in terms of effectiveness and safety. Conclusions: These findings underscore the treatment's effectiveness, safety, tolerability and positive influence on QoL in HD patients.

Keywords:
RWEeffectivenesshemorrhoidal diseasenatural substance-based medical devicereal-word evidencesafety

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