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Quality changes in animal feed resulting from extended storage.

W L Oller, D L Greenman, R Suber

    Laboratory Animal Science
    |December 1, 1985
    PubMed
    Summary

    Extended storage of autoclaved animal feed up to 130 days did not negatively impact feed quality or experimental mouse health. This finding supports longer storage durations for autoclaved feed, ensuring animal welfare and research integrity.

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    Area of Science:

    • Animal Science
    • Laboratory Animal Science
    • Food Science

    Background:

    • Autoclaving is a common method for sterilizing animal feed.
    • Concerns exist regarding the impact of extended storage on autoclaved feed quality.
    • Maintaining feed integrity is crucial for experimental animal welfare and research outcomes.

    Purpose of the Study:

    • To evaluate the effects of extended storage on autoclaved animal feed quality.
    • To determine if prolonged storage of autoclaved feed is detrimental to experimental animals.
    • To establish safe storage durations for autoclaved feed.

    Main Methods:

    • Fresh animal feed was autoclaved weekly and stored under controlled conditions (18.5 ± 2°C, 50 ± 5% RH).
    • Feed storage durations included 10, 74, and 130 days.
    • Weanling BALB/c and B6C3F1 mice were used, with measurements of food consumption, body weight, and serum protein levels over 13 weeks.

    Main Results:

    • No significant differences were observed in serum protein levels or weight ratios among the different feed storage groups.
    • Statistical analysis revealed interactions among gender, replication, and mouse genome, but not related to feed storage duration.
    • Histological examination of livers showed no signs of disease or nutritional disorders in any treatment group.

    Conclusions:

    • Autoclaved animal feed can be stored for up to 130 days without apparent adverse effects on the health or physiological parameters of BALB/c and B6C3F1 mice.
    • This study validates extended storage periods for autoclaved feed, potentially improving logistical efficiency in research facilities.
    • The findings support the use of longer-term storage of autoclaved feed, ensuring its quality and safety for experimental animals.

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