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The Total Artificial Heart: A Historical Perspective.
Daniele Masarone1, Rita Gravino1, Luigi Falco1
1Department of Cardiology, AORN dei Colli-Monaldi Hospital, 80131 Naples, Italy.
Journal of Clinical Medicine
|September 13, 2025
Summary
Developing total artificial hearts (TAHs) aims to bridge patients with advanced biventricular heart failure to transplantation. This review covers TAH history, current devices, and future innovations for life support.
Area of Science:
- Biomedical Engineering
- Cardiovascular Science
- Medical Devices
Background:
- Advanced biventricular heart failure necessitates mechanical circulatory support.
- Total artificial hearts (TAHs) serve as a bridge to transplantation.
- Significant progress has been made in TAH technology.
Purpose of the Study:
- To provide a historical overview of total artificial heart development.
- To analyze current total artificial heart devices.
- To discuss future innovations in TAH systems.
Main Methods:
- Literature review of historical and current total artificial heart research.
- Analysis of existing total artificial heart device designs and performance.
- Exploration of emerging technologies and future directions in the field.
Main Results:
- The evolution of total artificial hearts has progressed significantly.
- Current devices offer viable solutions for end-stage heart failure.
- Technological advancements promise improved future TAH systems.
Conclusions:
- Total artificial hearts are crucial for managing end-stage heart failure.
- Ongoing innovation is vital for enhancing patient outcomes.
- Future TAH systems are expected to offer greater reliability and functionality.
