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Heart Failure VI: Adjunct Therapies

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Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.

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Updated: Jan 18, 2026

Implantation of the Syncardia Total Artificial Heart

Implantation of the Syncardia Total Artificial Heart

Published on: July 18, 2014

The Total Artificial Heart: A Historical Perspective.

Daniele Masarone¹, Rita Gravino¹, Luigi Falco¹

¹Department of Cardiology, AORN dei Colli-Monaldi Hospital, 80131 Naples, Italy.

Journal of Clinical Medicine

|September 13, 2025

Summary

Developing total artificial hearts (TAHs) aims to bridge patients with advanced biventricular heart failure to transplantation. This review covers TAH history, current devices, and future innovations for life support.

Keywords:

advanced heart failure history of medicine total artificial heart

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Area of Science:

Biomedical Engineering
Cardiovascular Science
Medical Devices

Background:

Advanced biventricular heart failure necessitates mechanical circulatory support.
Total artificial hearts (TAHs) serve as a bridge to transplantation.
Significant progress has been made in TAH technology.

Purpose of the Study:

To provide a historical overview of total artificial heart development.
To analyze current total artificial heart devices.
To discuss future innovations in TAH systems.

Main Methods:

Literature review of historical and current total artificial heart research.
Analysis of existing total artificial heart device designs and performance.
Exploration of emerging technologies and future directions in the field.

Main Results:

The evolution of total artificial hearts has progressed significantly.
Current devices offer viable solutions for end-stage heart failure.
Technological advancements promise improved future TAH systems.

Conclusions:

Total artificial hearts are crucial for managing end-stage heart failure.
Ongoing innovation is vital for enhancing patient outcomes.
Future TAH systems are expected to offer greater reliability and functionality.