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Area of Science:

  • Infectious Diseases
  • Gastroenterology
  • Zoonotic Diseases

Background:

  • Leptospirosis is a prevalent zoonotic disease in tropical regions, particularly the Indian subcontinent.
  • It typically presents with fever, myalgia, and jaundice, but can manifest severely as vasculitis or Weil's disease.

Purpose of the Study:

  • To describe an atypical presentation of leptospirosis mimicking colonic malignancy.
  • To highlight the diagnostic challenges and importance of considering infectious etiologies in suspected cancers.

Main Methods:

  • Case report of a patient presenting with symptoms suggestive of colonic malignancy.
  • Diagnostic investigations including imaging and laboratory tests.
  • Confirmation of leptospiral infection and response to antibiotic therapy.

Main Results:

  • Initial suspicion of colonic malignancy with hepatic metastasis.
  • Investigation revealed an inflammatory mass in the descending colon.
  • The mass was confirmed as a leptospiral infection, responding to antibiotics.

Conclusions:

  • Leptospirosis can present atypically, mimicking colonic malignancy and causing diagnostic dilemmas.
  • This case underscores the importance of considering infectious causes, like leptospirosis, in patients with suspected gastrointestinal cancers, especially in endemic regions.