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Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

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Confined Assembly of Well-Defined Single-Unit Chain with Charge Delocalization for Boosting Catalysis.

Boyuan Yu¹, Zhen Yao¹, Zheyi Cheng¹

¹Department of Chemistry, Guangdong Provincial Key Laboratory of Catalysis, Southern University of Science and Technology, Shenzhen 518055, China.

Journal of the American Chemical Society

|September 13, 2025

Summary

Researchers developed single-unit-chain catalysts within carbon nanotubes, enhancing catalytic activity through charge delocalization. This stable, generalizable method boosts performance in various reactions.

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Controlling the Size, Shape and Stability of Supramolecular Polymers in Water

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Area of Science:

Materials Science
Catalysis
Nanotechnology

Background:

Single-atomic catalysts offer maximized performance via exposed sites and tailored electronic structures.
Synthesizing atomically precise, stable one-dimensional catalysts remains a significant challenge.

Purpose of the Study:

To develop a general strategy for fabricating stable single-unit-chain catalysts.
To investigate the role of charge delocalization in enhancing catalytic activity.

Main Methods:

Liquid-phase assembly to uniformly pack diverse clusters/atoms into ordered single-unit chains inside single-walled carbon nanotubes (SWCNTs).
Characterization of catalyst structure and electronic properties.
Evaluation of catalytic performance in redox and coupling reactions.

Main Results:

Successfully fabricated uniform single-unit chains of various catalysts within SWCNTs.
Achieved significant charge delocalization across SWCNT surfaces, tunable via catalyst-SWCNT interaction.
Demonstrated 7.5–28 times higher rate constants compared to isolated clusters.
Observed sustained high activity over 230 hours of continuous-flow reactions.

Conclusions:

Charge delocalization in SWCNT-confined single-unit-chain catalysts dramatically enhances activity and stability.
The developed liquid-phase assembly offers a versatile platform for diverse single-chain catalyst fabrication.
This approach presents a promising strategy for developing highly efficient and stable catalysts for practical applications.