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Gut microbiota: contributing to high CVD prevalence in people living with schizophrenia?
Chuanwen Fu1, Xuehui Zhang1, Ying Qian1
1Yunnan Provincial Key Laboratory of Public Health and Biosafety & School of Public Health, Kunming Medical University, Kunming, China.
Abstract:
People living with schizophrenia (PLWS) have a reduced life expectancy with cardiovascular disease (CVD) as a major contributor. This article reviews the existing populations and animal studies and summarizes that reduced abundance of Lachnospiraceae, Bacteroides, Faecalibacterium, Ruminococcus, Roseburia, Bifidobacterium, Lactobacillus, Akkermansia, Rikenellaceae and increased abundance of Prevotella, Clostridium, Escherichia in PLWS is one of the probable reasons for the increased risk of CVD prevalence in PLWS by affecting the metabolism of substances related to the development of Schizophrenia (SCZ) and CVD.
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