Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Microbial Biosensors

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Biosynthetic pathway construction and production enhancement of phenazine-1-carboxylic acid derivatives in Pseudomonas chlororaphis H18.

Microbial cell factories·2026

Same author

Comparing the efficacy and safety of medications to prevent nonsteroidal anti-inflammatory drug-induced ulcers in high-risk patients: A network meta-analysis.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2025

Same author

Changes in end-of-life care models among Chinese older adults, 1998-2018: an age-period-cohort analysis.

BMC geriatrics·2025

Same author

CATM: A Multi-Feature-Based Cross-Scale Attentional Convolutional EEG Emotion Recognition Model.

Sensors (Basel, Switzerland)·2024

Same author

Preoperative Prediction of Axillary Lymph Node Metastasis in Patients With Breast Cancer Through Multimodal Deep Learning Based on Ultrasound and Magnetic Resonance Imaging Images.

Academic radiology·2024

Same author

Finite element analysis of a novel anatomical plate in posterolateral plateau fractures.

Frontiers in surgery·2024

Search research articles

Related Experiment Video

Updated: May 1, 2026

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

YOLOv5-aided paper-based microfluidic intelligent sensing platform for multiplex sweat biomarker analysis.

Tengyun Li¹, Chenxi Gong¹, Jianhua Zhou²

¹School of Biomedical Engineering, Shenzhen Campus of Sun Yat-sen University, Shenzhen, 518107, China.

Biosensors & Bioelectronics

|September 13, 2025

Summary

We developed a smart, paper-based sensor for sweat analysis. This cost-effective platform uses smartphone imaging and AI for accurate, non-invasive health monitoring of multiple biomarkers.

Keywords:

Artificial intelligence Colorimetric analysis Microfluidics Multiplex biomarker Paper-based chip Sweat

More Related Videos

Fully Automated Centrifugal Microfluidic Device for Ultrasensitive Protein Detection from Whole Blood

Fully Automated Centrifugal Microfluidic Device for Ultrasensitive Protein Detection from Whole Blood

Published on: April 16, 2016

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

Related Experiment Videos

Last Updated: May 1, 2026

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

A Microfluidic Chip for the Versatile Chemical Analysis of Single Cells

Published on: October 15, 2013

Fully Automated Centrifugal Microfluidic Device for Ultrasensitive Protein Detection from Whole Blood

Fully Automated Centrifugal Microfluidic Device for Ultrasensitive Protein Detection from Whole Blood

Published on: April 16, 2016

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

Area of Science:

Biomedical Engineering
Analytical Chemistry
Point-of-Care Diagnostics

Background:

Sweat analysis offers non-invasive health monitoring potential.
Conventional sweat analysis methods face accuracy and complexity challenges.
Existing platforms struggle with scalability and resource limitations.

Purpose of the Study:

To develop an intelligent, paper-based microfluidic sensing platform for sweat biomarker detection.
To overcome limitations of conventional methods in accuracy, cost, and complexity.
To enable portable and reproducible point-of-care diagnostics.

Main Methods:

Integration of a paper-based microfluidic chip with smartphone imaging.
Utilization of a deep learning framework (YOLOv5) for image analysis.
Colorimetric detection of multiplex biomarkers in sweat samples.

Main Results:

The YOLOv5 deep learning model achieved a mean average precision of 99.5%.
Successful validation of the platform for detecting iron ions, chloride ions, and glucose in sweat.
Demonstration of a cost-effective, portable, and reproducible sensing system.

Conclusions:

The developed platform offers a promising solution for non-invasive sweat analysis.
This intelligent sensing system addresses key challenges in current point-of-care diagnostics.
The technology facilitates accessible health monitoring, particularly in resource-limited settings.