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Updated: Jan 17, 2026

Parallel Interrogation of β-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay
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Future Directions in GPCR Biased Signaling and Ligand Pharmacology

Dannya Estau1, Zijian Li2,3

  • 1Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital; Beijing Key Laboratory of Cardiovascular Receptors Research, State Key Laboratory of Vascular Homeostasis and Remodeling, and NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Peking University; Research Unit of Medical Science Research Management/Basic and Clinical Research of Metabolic Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking University, Beijing, China.

Handbook of Experimental Pharmacology
|September 14, 2025
PubMed
Abstract

Keywords:
Biased signalingFuture directionsG protein-coupled receptorLigand pharmacology

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