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Updated: Jan 17, 2026

Isolation and Characterization of Neutrophils with Anti-Tumor Properties
Published on: June 19, 2015
TRPV2 Regulates Function of Human Neutrophil Granulocytes
Anna S Heinemann1, Tabea C Fricke1, Christine Herzog1
1Department of Anesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany.
Abstract:
Neutrophils play a vital role in human immune defense, and their dysregulation can cause collateral damage in sepsis and autoimmune diseases. We provide evidence for the involvement of the transient receptor potential vanilloid 2 (TRPV2) in cytokine expression and transmigration in human neutrophils as well as in HL60 cells. These data identify TRPV2 as a candidate target for novel therapeutics regulating neutrophil activity.
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