Related Experiment Video
Updated: Jan 17, 2026
06:35
Construction and Systematical Symmetric Studies of a Series of Supramolecular Clusters with Binary or Ternary Ammonium Triphenylacetates
Published on: February 15, 2016
8.5K
Organic Salts as Supramolecular Hosts with Various Applications.
Abhay Pratap Singh1, Jubaraj B Baruah1
1Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, Assam 781 039, India.
ACS Omega
|September 15, 2025
Summary
Ionic cocrystals, formed from Brønsted salts, offer versatile applications in medicine, energy, and materials. These hydrogen-bonded assemblies enable control over component delivery and properties.
Area of Science:
- Supramolecular Chemistry
- Materials Science
- Crystallography
Background:
- Brønsted salts are fundamental in various scientific fields.
- Ionic cocrystals are formed through the self-assembly of Brønsted salts with neutral components.
- These compounds exhibit potential in diverse applications.
Purpose of the Study:
- To explore hydrogen-bonded assemblies of host-guest complexes of organic salts, termed ionic cocrystals.
- To analyze the structural features and self-recognition capabilities of ionic cocrystals.
- To present the perspectives of ionic cocrystals in energy, medicine, environment, and materials science.
Main Methods:
- Review of literature on Brønsted salts and ionic cocrystals.
- Analysis of structural compositions and types of salt cocrystals.
- Discussion of self-assembly mechanisms and host-guest interactions.
Main Results:
- Ionic cocrystals demonstrate significant potential in controlling bioavailability, degradation, and targeted delivery.
- The study illustrates various compositions and types of salt cocrystals, highlighting key structural features.
- Analysis confirms the utility of Brønsted salt host systems in molecular recognition and self-recognition.
Conclusions:
- Ionic cocrystals represent a promising class of materials with broad applicability.
- Their tunable properties make them valuable for advancements in medicine, energy, and materials science.
- Further research into their self-assembly and recognition mechanisms can unlock new applications.
Related Concept Videos
02:51Metal-Ligand Bonds
24.0K
The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
24.0K
02:34Nucleophilic Substitution Reactions
19.1K
Historical perspective
In 1896, the German chemist Paul Walden discovered that he could interconvert pure enantiomeric (+) and (-) malic acids through a series of reactions. This conversion suggested the involvement of optical inversion during the substitution reaction. Further, in 1930, Sir Christopher Ingold described for the first time two different forms of nucleophilic substitution reactions, which are known as SN1 (nucleophilic substitution unimolecular) and SN2 (nucleophilic substitution...
In 1896, the German chemist Paul Walden discovered that he could interconvert pure enantiomeric (+) and (-) malic acids through a series of reactions. This conversion suggested the involvement of optical inversion during the substitution reaction. Further, in 1930, Sir Christopher Ingold described for the first time two different forms of nucleophilic substitution reactions, which are known as SN1 (nucleophilic substitution unimolecular) and SN2 (nucleophilic substitution...
19.1K
01:22EDTA: Chemistry and Properties
3.3K
Polydentate ligands are most widely used in complexometric titrations because they form more stable complexes with the metal ions than mono- or bidentate ligands due to the chelate effect. Examples of polydentate ligands are ethylenediaminetetraacetic acid (EDTA), crown ethers, and cryptands. The most important feature of optimal polydentate ligands is the ability to form 1:1 complexes in a single-step process. Amino carboxylic acid derivatives are frequently used as complexing agents. EDTA is...
3.3K
01:23Properties of Organometallic Compounds
1.6K
Organometallic compounds are compounds that contain a carbon–metal bond. Carbon belongs to an organyl group like alkyl, aryl, allyl, or benzyl groups. The metal can be from Group I or Group II of the periodic table, a transition metal, or a semimetal.
1.6K
01:19Complexation Equilibria: The Chelate Effect
1.2K
In complexation reactions, metal atoms or cations interact with ligands to form donor-acceptor adducts called metal complexes. Ligands that bind through one donor site are monodentate, ligands with two donor sites are bidentate, and those with more than two donor sites are polydentate ligands. For example, ethylene diamine is a bidentate ligand that binds through two nitrogen donor atoms, forming a five-membered ring. EDTA is a polydentate ligand that binds through four oxygen and two nitrogen...
1.2K
00:49Gravimetry: Inorganic And Organic Precipitating Agents
6.2K
In gravimetry, the precipitant is chosen carefully to obtain a pure solid that can be easily filtered. Common inorganic precipitants can be used to determine several cations and anions. In some cases, the formation of the same precipitate can be used to determine the cation and the anion. For example, the reaction of barium and chromate ions to give barium chromate is used to determine both barium and chromate. However, precipitates such as hydroxides, oxalates, and metal ammonium phosphates...
6.2K