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Updated: May 5, 2026

The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation
Published on: January 31, 2025
Transforming biliary surgery: Innovations in fluorescence-guided imaging and indocyanine green application.
Thai-Hau Koo1, Xue-Bin Leong2, Yi-Lin Lee2
1Department of Internal Medicine, School of Medical Sciences and Hospital Universiti Sains Malaysia, Kota Bharu 16150, Kelantan, Malaysia.
Multicolor near-infrared fluorescence imaging (MCFI) improves visualization during laparoscopic cholecystectomy by using indocyanine green. This advanced technique enhances biliary structure clarity and reduces surgeon visual fatigue compared to single-color methods.
Area of Science:
- Surgical Innovation
- Medical Imaging
- Gastroenterology
Background:
- Conventional single-color fluorescence imaging (SCFI) in laparoscopic cholecystectomy presents limitations.
- SCFI's reliance on a single green signal causes visual fatigue and difficulty distinguishing biliary anatomy.
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