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Postoperative infection following anterior cervical fusion surgery caused by Prevotella oris: a case report
1Spinal Surgery Department, Mianyang Orthopaedic Hospital, Mianyang, Sichuan, China.
Abstract:
Postoperative infections following spinal fusion procedures are commonly caused by pathogens such as Staphylococcus aureus, coagulase-negative Staphylococcus, Streptococcus species, and Escherichia coli. However, cases involving Prevotella oris as a causative agent are rarely documented in the literature. We report a case of postoperative infection after anterior cervical spinal fusion surgery. After empirical antimicrobial therapy failed, high-throughput nucleic acid sequencing detected Prevotella oris in the patient's cerebrospinal fluid-a rare and previously unreported finding. Upon switching to a more sensitive antibiotic regimen, the patient's symptoms improved significantly. This case highlights an unusual etiology and provides a comprehensive documentation of the treatment process, aiming to assist clinicians in the diagnosis and management of similar infections.
Insights
Postoperative spinal fusion infections are usually bacterial. This case details a rare Prevotella oris infection, successfully treated after initial therapy failed, highlighting a new diagnostic approach.
Area of Science:
- Infectious Diseases
- Neurosurgery
- Microbiology
Background:
- Postoperative spinal fusion infections commonly involve Staphylococcus and Streptococcus species.
- Prevotella oris is a rarely reported causative agent of such infections.
- Standard antimicrobial therapies may not always be effective against unusual pathogens.
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