Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

228
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
228
Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

643
Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
643
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

238
In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
238
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

232
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
232
Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

726
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
726
Drugs Affecting GI Tract Motility: Other Laxatives01:20

Drugs Affecting GI Tract Motility: Other Laxatives

1.0K
Laxatives are primarily used to alleviate constipation, a common gastrointestinal disorder characterized by infrequent bowel movements and difficulty passing stools. They work by various mechanisms to increase the volume or frequency of bowel movements. The primary modes of action of laxatives include increasing stool bulk, softening the stool, stimulating intestinal motility, and osmotically drawing water into the intestines.
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identification of genetic modifiers of autosomal dominant Alzheimer's disease: a genome-wide association study.

The Lancet. Neurology·2026
Same author

Inhibitory potential of Malabaricone C and Quercetagetin against aberrantly expressed Maternal Embryonic Leucine Zipper Kinase using integrated virtual screening, molecular dynamics and MMGBSA approach.

In silico pharmacology·2025
Same author

Clinical Setting Does Not Impact Baseline Patient Reported Outcomes Measures in Patients Undergoing Anterior Cervical Diskectomy and Fusion: A Prospective Study.

Journal of clinical medicine·2025
Same author

HIV and Non-HIV Patients Have Similar Rates of Neoplastic Findings on Screening Colonoscopy Within a Predominantly African American Cohort.

Cancer medicine·2025
Same author

Proton pump inhibitor dosing patterns are less than optimal among new referrals to an outpatient gastroenterology clinic.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·2025
Same author

Whole-genome sequencing reveals the impact of lipid pathway and APOE genotype on brain amyloidosis.

Human molecular genetics·2025
Same journal

iCare Compassionately: An Innovative Approach to Improving Nursing Education.

HCA healthcare journal of medicine·2026
Same journal

A Scalable Model for Resident and Faculty Well-Being: Applying Self-Determination Theory and the Job Demands-Resources Framework in Graduate Medical Education.

HCA healthcare journal of medicine·2026
Same journal

The Distinguished Humanitarian Society.

HCA healthcare journal of medicine·2026
Same journal

Optimizing Antibiotic Strategies With a Clinical Pathway Approach: Enhanced Initiation and De-escalation in Community-Acquired Pneumonia.

HCA healthcare journal of medicine·2026
Same journal

Under Chiron's Care.

HCA healthcare journal of medicine·2026
Same journal

Establishing Nurse Innovator Competencies: A Collaborative Initiative.

HCA healthcare journal of medicine·2026
See all related articles

Related Experiment Video

Updated: Jan 17, 2026

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease
03:50

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease

Published on: August 18, 2023

2.7K

A Hard Problem: Managing Constipation in the Geriatric Population.

William G Jones1, Veeraen Jonnalagadda1, Alexandra E Thomson1

  • 1Memorial Health University Medical Center, Savannah, Georgia.

HCA Healthcare Journal of Medicine
|September 15, 2025
PubMed
Summary
This summary is machine-generated.

Managing constipation in geriatric patients is crucial due to potential complications and healthcare burden. This summary offers prevention and management strategies for older adults, aiding healthcare providers.

Keywords:
constipation, constipationdiet therapy, constipationdrug therapy, dietary fiber, laxatives, aged, elderlyprevention and control, constipation

More Related Videos

Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation
04:04

Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation

Published on: July 5, 2024

955
Author Spotlight: Exploring Non-Pharmacological Therapies for Chronic Respiratory Diseases — Linking Intestinal Microbiome Insights to COPD Treatment
03:25

Author Spotlight: Exploring Non-Pharmacological Therapies for Chronic Respiratory Diseases — Linking Intestinal Microbiome Insights to COPD Treatment

Published on: December 27, 2024

1.5K

Related Experiment Videos

Last Updated: Jan 17, 2026

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease
03:50

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease

Published on: August 18, 2023

2.7K
Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation
04:04

Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation

Published on: July 5, 2024

955
Author Spotlight: Exploring Non-Pharmacological Therapies for Chronic Respiratory Diseases — Linking Intestinal Microbiome Insights to COPD Treatment
03:25

Author Spotlight: Exploring Non-Pharmacological Therapies for Chronic Respiratory Diseases — Linking Intestinal Microbiome Insights to COPD Treatment

Published on: December 27, 2024

1.5K

Area of Science:

  • Geriatric Medicine
  • Gastroenterology

Background:

  • Constipation is a prevalent condition in geriatric patients, presenting diverse symptoms and risks.
  • It imposes a substantial burden on healthcare systems.

Purpose of the Study:

  • To provide guidance on managing constipation in geriatric patients.
  • To emphasize prevention strategies for constipation in older adults.
  • To outline management approaches across various healthcare settings.

Main Methods:

  • Summarized recommendations from major medical societies.
  • Included guidelines from the American College of Gastroenterology, American Geriatrics Society, and American Academy of Family Physicians.

Main Results:

  • Consensus-based recommendations for constipation prevention in the elderly.
  • Strategies for managing constipation once it develops in geriatric patients.
  • Guidance applicable to different healthcare environments.

Conclusions:

  • Effective management and prevention of constipation are vital in geriatric care.
  • These recommendations support healthcare providers in addressing this common issue.
  • Proactive management can alleviate the burden of constipation on patients and the healthcare system.