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Zolpidem restores sleep and slows Alzheimer's progression in a mouse model

Lu Yu1,2, Shinya Yokomizo1, Tri H Doan1

  • 1Department of Neurology, MassGeneral Institute of Neurodegenerative Diseases, Mass General Brigham and Harvard Medical School, 114 16th Street, Charlestown, MA 02129, USA.

Biorxiv : the Preprint Server for Biology
|September 15, 2025
PubMed
Abstract

Keywords:
APP/PS1 miceAlzheimer’s diseaseAmyloid plaquesCalcium homeostasisGABAA receptorMemory consolidationNREM sleepNeurodegenerationSleepSlow oscillationZolpidem

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