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Meningococcal Septic Shock Revealed: The Frightening Face of Serogroup B
Belkis Hatice Inceli1, Döndü Nilay Penezoglu2, Merve Havan3
1Pediatric Infectious Diseases, Ankara University School of Medicine, Ankara, TUR.
Abstract:
Meningococcal infections are still a serious cause of morbidity and mortality in children, despite vaccine developments or advancements in vaccination, antibiotics, supportive treatments, and advancements in intensive care facilities. Neisseria meningitidis has 12 serogroups, among which A, B, C, Y, and W are responsible for the most invasive infections. Sudden onset, rapid worsening, and high contagiousness are important clinical features of meningococcal infections. Purpura fulminans, septic shock, multiple organ failure, and increased intracranial pressure also constitute life-threatening complications. Here, we present a six-month-old female patient who presented with complaints of fever, malaise, and rash and was diagnosed with meningococcal sepsis and shock based on clinical examination, laboratory findings, and blood polymerase chain reaction (PCR) positivity. She was treated in the pediatric intensive care unit (PICU) but died despite the treatments.
Insights
Meningococcal infections remain a severe threat to children, causing significant illness and death. A six-month-old infant with meningococcal sepsis and shock died despite intensive care, highlighting the disease
Area of Science:
- Pediatrics
- Infectious Diseases
- Microbiology
Background:
- Meningococcal infections caused by *Neisseria meningitidis* are a major cause of child morbidity and mortality.
- Despite advances in vaccines, antibiotics, and intensive care, invasive meningococcal disease remains a critical health concern.
- Key serogroups A, B, C, Y, and W are associated with the most severe invasive infections.
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