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Related Concept Videos

Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

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Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
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Cardiac Catheterization IV: Nursing Management01:26

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Nursing responsibilities before cardiac catheterization include:Assess for allergies and establish baseline health status.Before cardiac catheterization, assess the patient for allergies to contrast dye. Perform a comprehensive baseline assessment, including vital signs, heart and breath sounds, and a neurovascular assessment of the extremities, noting distal pulses, skin color, and temperature. Instruct the patient to fast for 8-12 hours before the procedure. Evaluate baseline laboratory...
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Imaging Studies VII: Vascular Imaging01:19

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DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
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Imaging Studies III: Computed Tomography01:27

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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Imaging Studies I: CT and MRI01:14

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Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
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Radiological Investigation I: X-ray and CT01:30

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Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
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Addressing Stroke Care: Overcoming Contrast-Allergy Challenges With Rapid Intravenous Dye Preparation.

Karen Greenberg1, Jennifer A Ross1, Thomas A Kurtz1

  • 1Neurosciences, Global Neurosciences Institute, Pennington, USA.

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|September 15, 2025
PubMed
Summary

A new protocol using IV dye preparation safely enabled timely neuroimaging for acute stroke patients with contrast allergies. This approach improved the detection of large-vessel occlusions, crucial for stroke treatment.

Keywords:
acute ischemic strokecomputed tomography angiography (cta)emergent neuroimaging protocolslarge vessel occlusion detectionradiocontrast media allergy

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Area of Science:

  • Neurology
  • Radiology
  • Emergency Medicine

Background:

  • Hypersensitivity reactions to iodinated contrast media complicate urgent neuroimaging in acute stroke patients.
  • Limited protocols exist for managing contrast allergies in emergent stroke care.

Purpose of the Study:

  • To assess the safety and efficacy of an emergent intravenous (IV) dye preparation protocol for stroke patients with known contrast allergies.
  • To enable timely neuroimaging in high-risk patients.

Main Methods:

  • Retrospective review of stroke-alert patients (2021-2023) with documented IV dye allergies (excluding anaphylaxis/airway edema).
  • Administered emergent IV dye preparation: diphenhydramine, famotidine, and dexamethasone before CT angiography (CTA) or CT perfusion (CTP).
  • Analyzed data using descriptive statistics and chi-square tests (P < 0.05).

Main Results:

  • 5.8% of 1,001 stroke patients had contrast allergies; 25 received emergent imaging.
  • No adverse reactions occurred within 24 hours post-imaging.
  • Improved detection of large vessel occlusions (LVO) or severe carotid stenosis in the contrast group (24%) vs. non-contrast (7.7%).

Conclusions:

  • The emergent IV dye preparation protocol is safe and effective for acute stroke patients with contrast allergies.
  • This protocol facilitates timely neuroimaging, improving the detection of treatable LVOs.
  • The number needed to treat to detect one additional LVO was six.