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Outcomes of Paediatric Glaucoma Surgery: Insights From a Five-Year Retrospective Study in Manchester

Elpida Kollia1,2,3, Bhamy Hariprasad Shenoy2, Vinod Sharma2

  • 1Paediatric Ophthalmology, Moorfields Eye Hospital, London, GBR.

Cureus
|September 15, 2025
PubMed

Insights

Surgical management of primary congenital glaucoma (PCG) in children led to favorable outcomes, including reduced eye pressure and improved optic nerve health. Early diagnosis and prompt surgery are vital for preventing vision loss in PCG patients.

Area of Science:

  • Ophthalmology
  • Paediatric Surgery

Background:

  • Primary congenital glaucoma (PCG) is a rare, severe form of glaucoma present at birth.
  • Timely intervention is critical to prevent irreversible vision loss.

Purpose of the Study:

  • To evaluate the clinical outcomes of surgical interventions for PCG.
  • To assess the effectiveness of glaucoma surgery in a UK tertiary care setting.

Main Methods:

  • Retrospective analysis of 18 children (31 eyes) with PCG treated between 2019 and 2024.
  • Data collected included clinical characteristics, surgical procedures, intraocular pressure (IOP), and optic nerve status.

Main Results:

  • Mean age at diagnosis was 14 months; 13 children had bilateral PCG.
  • Surgical treatment significantly reduced IOP and corneal diameter, with optic disc cupping reversal in most cases.
  • Only 2 eyes required reoperation, and no significant intraoperative complications were noted.

Conclusions:

  • Surgical management of PCG at a tertiary center yields favorable anatomical and functional results.
  • A low reoperation rate was observed, highlighting surgical efficacy.
  • Early diagnosis and prompt surgical intervention are essential for preserving vision in children with PCG.
Abstract

Keywords:
intraocular pressureitrackpaediatric glaucoma surgeryprimary congenital glaucomatrabeculectomy blebtrabeculotomy

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