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Related Concept Videos

Oligosaccharide Assembly01:24

Oligosaccharide Assembly

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Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
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Protein Glycosylation01:25

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Glycosylation, the most common post-translational modification for proteins, serves diverse functions. Adding sugars to proteins makes the proteins more resistant to proteolytic digestion. Glycosylated proteins can act as markers and receptors to promote cell-cell adhesion. Additionally, they have many essential quality control functions in the cell, such as correct protein folding and facilitating transport of misfolded proteins to the cytosol, which can be degraded.
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Biosynthesis of Polysaccharides01:26

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Polysaccharides such as glycogen and starch are synthesized from nucleoside diphosphate sugars, primarily uridine diphosphate glucose (UDPG) and adenosine diphosphate glucose (ADPG). These activated glucose donors act as key intermediates in carbohydrate metabolism and biosynthesis. UDPG primarily involves glycogen synthesis in animals and many bacteria, while ADPG plays a fundamental role in starch synthesis in plants and certain bacteria.UDPG is formed when glucose-1-phosphate reacts with...
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Role of Septins01:02

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Septins are the recently discovered fourth major protein component of the cytoskeleton, along with microfilaments, microtubules, and intermediate filaments. These proteins can associate with other cytoskeletal filaments and carry out varied roles or can be free-floating in the cytoplasm.
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Related Experiment Video

Updated: Jan 17, 2026

Comparative Study on the Polysaccharide Contents and Antioxidant Activities of Hippophae rhamnoides subsp. sinensis and Hippophae gyantsensis
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Selenium-Polysaccharides: Structural Characterization, Biological Activities, and Emerging Applications.

Shahidin1,2, Yilong Wu1,2, Yan Wang1,2

  • 1Key Laboratory of Pu-erh Tea Science, Ministry of Education, College of Food Science and Technology Yunnan Agricultural University Kunming China.

Food Science & Nutrition
|September 15, 2025
PubMed
Summary
This summary is machine-generated.

Selenium-polysaccharides (SePs) offer enhanced biological activity for nutraceuticals. This study explores their biosynthetic pathways, structure-activity relationships, and applications, highlighting their health benefits.

Keywords:
biological activitiesbiosynthetic pathwayemerging applicationspreparationselenium‐polysaccharidesstructural characterizationstructure–activity relationship

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Area of Science:

  • Biochemistry and Nutraceutical Science
  • Exploration of bioactive compounds and their health benefits.

Background:

  • Selenium-polysaccharides (SePs) are formed by incorporating selenium into polysaccharides, enhancing biological activity.
  • Structural variations in SePs influence their diverse biological effects, including antioxidant and anti-cancer properties.
  • SePs show promise for nutraceutical applications due to their health benefits.

Purpose of the Study:

  • Investigate the biosynthetic pathways of SePs in plants.
  • Elucidate the structure-activity relationships of SePs.
  • Explore emerging therapeutic and industrial applications of SePs.

Main Methods:

  • Review of existing literature on SeP extraction and selenylation.
  • Analysis of structural variations and their impact on biological activity.
  • Identification of knowledge gaps in SeP biosynthesis and applications.

Main Results:

  • SePs exhibit significant antioxidant, anti-cancer, immune-regulating, and anti-inflammatory activities.
  • Structural modifications in SePs are key to their enhanced bioactivity.
  • Further research is needed on Se dynamics, biosynthetic pathways, and specific applications.

Conclusions:

  • SePs are promising bioactive compounds with diverse health benefits.
  • Understanding SeP biosynthesis and structure-activity relationships is crucial for optimizing their applications.
  • SePs hold potential for the food and health industries, warranting further investigation.