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Lung abscess and empyema.

J E Neild, S J Eykyn, I Phillips

    The Quarterly Journal of Medicine
    |December 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    This study on lung abscess and empyema found that while many bacteria were cultured, penicillin resistance was common. Appropriate antibiotics and drainage are key, as penicillin is no longer the primary choice.

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    Area of Science:

    • Pulmonology
    • Infectious Diseases
    • Microbiology

    Background:

    • Lung abscess and empyema are serious thoracic infections.
    • Understanding causative organisms and effective treatments is crucial for patient outcomes.

    Purpose of the Study:

    • To review clinical features, diagnostics, and management of lung abscess and empyema.
    • To assess the microbiological profile and antibiotic susceptibility in these infections.

    Main Methods:

    • Retrospective study of 48 patients with lung abscess or empyema (1976-1984).
    • Analysis of clinical data, microbiological cultures, and treatment outcomes.

    Main Results:

    • Mixed aerobic and anaerobic infections were most common (54.2%).

    Related Experiment Videos

  • Significant penicillin resistance observed in both aerobic (45%) and anaerobic (17.8%) bacteria.
  • No distinct clinical features differentiated lung abscess from empyema or infection origin.

    • Conclusions:

    • Medical management with antibiotics and physiotherapy is recommended for lung abscess.
    • Penicillin is no longer the preferred antibiotic; broader-spectrum agents are necessary.
    • Failure to drain warrants investigation for underlying abnormalities like tumors.