Clinical Reasoning: A 73-Year-Old Man With Progressive Proximal Muscle Weakness and Binocular Diplopia
Karl J Wold1, Armand Amini2, David Bargiela1
1Department of Neurology, Mass General Brigham, Boston, MA; and.
Abstract:
Progressive weakness and diplopia have a wide differential diagnosis, which can be narrowed by obtaining a detailed history and performing a careful physical examination. It is essential to determine whether these 2 symptoms are due to a single, unifying process or separate processes. We review the case of a 73-year-old man with progressive proximal lower than upper extremity weakness, followed by binocular horizontal diplopia. Clinical history, with attention to rate of progression and associated symptomatology, guided our diagnostic approach and final diagnosis.
More Related Videos
07:00Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis
Published on: October 13, 2016
11:12Driving Simulation in the Clinic: Testing Visual Exploratory Behavior in Daily Life Activities in Patients with Visual Field Defects
Published on: September 18, 2012
Related Concept Videos
Photoreceptors and Visual Pathways
Myasthenia Gravis: Diagnostic Tests
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
Accessory Structures of the Eye
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Glaucoma: Overview
Myasthenia Gravis: Overview and Treatment
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
