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Updated: Jan 17, 2026

Application of an Amplitude-integrated EEG Monitor Cerebral Function Monitor to Neonates
Published on: September 6, 2017
Electronic Fetal Monitoring Patterns With and Without Continuous Amnioinfusion
Brock E Polnaszek1,2, Jessica Chen1, Rodolfo Fernandez-Criado1
1Warren Alpert Medical School of Brown University, Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Women and Infants Hospital, Providence, Rhode Island.
Background:
This pre-specified analysis of a randomized controlled trial compared electronic fetal monitoring patterns among participants with and without amnioinfusion.
Methods:
Data from the parent randomized trial included 26 term singleton nulliparous participants who developed risk factors for fetal neurologic injury. For this secondary analysis, the primary outcome was total deceleration area-a pattern predictive of neonatal acidemia and morbidity. Secondary outcomes included electronic fetal monitoring patterns (eg, variability).
Results:
There were no differences in total deceleration area between the no amnioinfusion group and the amnioinfusion group (28 550 [8800-57 400] mm² [IQR] vs 31 500 [21 700-47 785] mm² [IQR], respectively; P = .84). Specific secondary outcomes differed by amnioinfusion.
Conclusions:
These results highlight the need for prospective data to identify the optimal amnioinfusion administration technique that reduces morbidity.
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