How to Manage Cardiovascular Disease in Psoriatic Disease: Evidence and Time Management in Clinic

Maria-Angeliki Gkini1, Pamela Diaz2, Cheryl F Rosen3

  • 1M.A. Gkini, MD, MSc, PhD, Department of Dermatology, Barts Health NHS Trust, London, UK; Maria-Angeliki.Gkini@nhs.net pjdiaz@uc.cl.

The Journal of Rheumatology
|September 15, 2025
PubMed

Insights

Early cardiovascular disease (CVD) recognition is vital for patients with psoriatic disease (PsD). Comprehensive assessment and management, involving multiple specialists, are crucial for preventing morbidity and mortality, despite practical challenges.

Area of Science:

  • Rheumatology
  • Cardiology
  • Dermatology

Background:

  • Psoriatic disease (PsD) and cardiovascular disease (CVD) share inflammatory pathways, increasing patient risk.
  • Early identification and management of CVD in PsD patients are critical for reducing morbidity and mortality.

Purpose of the Study:

  • To highlight the importance of cardiovascular risk assessment in psoriatic disease patients.
  • To outline strategies for the comprehensive management of cardiovascular comorbidities in PsD.

Main Methods:

  • Review of shared pathogenic mechanisms between PsD and CVD.
  • Assessment strategies including clinical history, risk factors, blood tests, and imaging.
  • Multidisciplinary approach involving primary care, internal medicine, cardiology, dermatology, and rheumatology.

Main Results:

  • PsD and CVD share proinflammatory cytokine pathways (e.g., tumor necrosis factor).
  • Comprehensive assessment should include clinical evaluation, risk factors (diabetes, hypertension, dyslipidemia), and diagnostic tests.
  • Multidisciplinary management and lifestyle interventions are essential.

Conclusions:

  • Routine cardiovascular assessment and management are recommended for all PsD patients.
  • Effective management requires collaboration among various medical specialists and addressing practical challenges.
  • Further research is needed to clarify CVD risk modification with PsD treatment remission.

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