Related Experiment Video
Updated: May 7, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
Published on: July 22, 2021
[Partial knee arthroplasty: development, current status and future perspectives]
Y L Xiong1, Y L Wang1, C Zeng1
1Department of Orthopaedics, Xiangya Hospital, Central South University, Key Laboratory of Aging-Related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Hunan Key Laboratory of Joint Degeneration and Injury, National Clinical Research Center for Geriatric Disorders (Xiangya Hospital), Changsha 410008, China.
Abstract:
Severe knee joint diseases, such as advanced knee osteoarthritis, often require total knee arthroplasty (TKA) for treatment. However, knee osteoarthritis typically affects only one or two compartments of the knee joint, and TKA inevitably involves the resection and reconstruction of healthy joint compartments. Partial knee arthroplasty (PKA) was developed as a targeted alternative, and after decades of advancement, it has become increasingly refined, demonstrating unique advantages in treating unicompartmental and/or bicompartmental knee joint diseases. This paper focuses on the development and current status of PKA, including unicondylar knee arthroplasty, patellofemoral arthroplasty, and bicompartmental knee arthroplasty. It summarizes patient selection criteria, clinical outcomes, and proposes future directions for further advancements.
Related Concept Videos
Knee Joint
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
Development of the Limb Synovial Joints
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...

