Multiple comorbidities and economic burden of hospitalized gout patients in Guangdong Province
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Jie Ren1, Xuantao Yan1, Shan Zeng1
1Department of Rheumatology and Immunology, the First Affiliated Hospital, Jinan University, Guangzhou, Guangdong, China.
Insights
Gout patients increasingly experience multiple health conditions, particularly women, with rising prevalence and high hospital costs. Acute gout cases show a downward cost trend for females.
Area of Science:
- Rheumatology
- Public Health
- Health Economics
Background:
- Gout is a prevalent condition with significant comorbidity and economic impact.
- Understanding comorbidity patterns and costs in gout patients is crucial for healthcare management.
Purpose of the Study:
- To analyze the prevalence of single and multiple comorbidities in hospitalized gout patients.
- To investigate the economic burden associated with gout hospitalization in Guangdong Province.
Main Methods:
- Retrieved data from 593,792 hospitalized gout patients in Guangdong Province (2015-2021).
- Analyzed comorbidity prevalence, focusing on single vs. multiple conditions.
- Assessed the economic burden, including average annual hospitalization costs.
Main Results:
- Gout prevalence was 1.31%, with males affected five times more than females.
- Hypertension, type 2 diabetes, and hyperlipidemia were the most common comorbidities.
- Multiple comorbidities, especially gout-hypertension-type 2 diabetes, showed an increasing trend and were more prevalent in women.
- Average annual costs for acute gouty arthritis ranged from RMB 5994.45 to RMB 6709.66, with higher costs for men and decreasing costs for women.
Conclusions:
- Gout patients frequently present with single and multiple comorbidities, with a notable increase in prevalence among women.
- Hospitalization costs for acute gout are substantial, though a downward trend was observed in female patients.
Introduction:
This study aimed to analyze the prevalence of multiple comorbidities and economic burden of hospitalized patients with gout in Guangdong Province.
Methods:
We retrieved the homepage information of 593,792 hospitalized patients with gout from January 1, 2015 to December 31, 2021 through the Guangdong Provincial Medical Record Homepage System and analyzed the prevalence of single comorbidity and multiple comorbidities and economic burden.
Results:
1. The prevalence of gout was 1.31%. The prevalence in males was five times higher than that of females. 2. The prevalence of hypertension was highest (42.59%) in gout patients; the following were type 2 diabetes (18.03%) and hyperlipidemia (17.98%). 3. The prevalence of hypertension, hyperlipidemia, type 2 diabetes, chronic heart failure, coronary heart disease, and chronic kidney disease were more prevalent in women (P < 0.05). 4. Gout-hypertension-type 2 diabetes had the highest prevalence in all gout patients. The prevalence of multiple complications showed an increasing trend. 5. Gout- hypertension-type 2 diabetes had the highest prevalence in male and female patients (P < 0.001). Except for the prevalence of gout-hypertension-obesity, gout-obesity-type 2 diabetes and gout-hypertension-obesity-type 2 diabetes, the prevalence of other multiple comorbidities was significantly higher in women (P < 0.001). 6. The average annual cost of hospitalized patients with acute gouty arthritis ranged from RMB 5994.45 to RMB 6709.66, which decreased in women. From 2020 to 2021, the average cost of men with acute gout was much higher than that of women. From 2018 to 2021, the average cost was highest in patients among 40-69 years old.
Conclusions:
1. Gout patients often have single and multiple comorbidities with a higher prevalence in women, and the prevalence showed an increasing trend. 2. Acute gout patients had high hospital costs, and female patients showed a downward trend. Key points • Gout patients have increasing single and multiple comorbidities with a higher prevalence in women. • Acute gout patients had high hospital costs, and female patients showed a downward trend.
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