A Retrospective Audit of Statin Prescription Practices in Diabetic Patients With Cardiovascular Risk

Muhammad Adnan Khaliq1, Sabih Nofal2, Samia Israr3

  • 1Internal Medicine, Services Hospital, Lahore, PAK.

Cureus
|September 16, 2025
PubMed

Insights

Diabetic patients often don't receive guideline-recommended statin therapy, leading to underuse and suboptimal dosing, particularly in women and younger individuals. Improving adherence is crucial for preventing cardiovascular disease in this high-risk population.

Area of Science:

  • Cardiology
  • Endocrinology
  • Public Health

Background:

  • Diabetic patients face elevated cardiovascular disease (CVD) risk.
  • Guidelines recommend statin therapy for most diabetics aged ≥40 or with established atherosclerotic CVD (ASCVD).

Purpose of the Study:

  • To audit adherence to guideline-based statin prescribing for diabetic patients with cardiovascular risk.
  • To identify gaps in statin prescription intensity and eligibility.

Main Methods:

  • Retrospective audit of 131 diabetic patients' medical records.
  • Data collected included demographics, diabetes duration, comorbidities, lipid profiles, CVD history, and statin prescription details.

Main Results:

  • 83.2% of diabetic patients were eligible for statin therapy; 77.1% received statins, but 22.9% remained untreated.
  • High-intensity statins were prescribed in only 33.3% of eligible cases.
  • Statin use was lower in females (69.2%) vs. males (83.8%) and younger patients.

Conclusions:

  • Significant underutilization and suboptimal dosing of statins observed in diabetic patients.
  • Gaps in adherence are notable, especially for women and younger individuals.
  • Enhanced clinical adherence strategies are needed to improve CVD outcomes.

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