Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

574
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
574

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Histomorphologic characteristics of abdominal aortic aneurysm samples are similar in abdominal-only vs thoracoabdominal involvement.

JVS-vascular science·2026
Same author

Health-related quality of life among patients with colorectal und pancreatic cancer: results from a monocentric registry study.

Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))·2026
Same author

From Guidelines to Practice: Regionalising Oncological Patient Pathways.

Studies in health technology and informatics·2026
Same author

CT-based muscle mass cutoff values for Caucasians according to the European Working Group on Sarcopenia recommendations.

European radiology·2026
Same author

[Open Thoracoabdominal Aortic Replacement for Midaortic Syndrome and COL3A1 Variant].

Zentralblatt fur Chirurgie·2026
Same author

Intratumoral regulatory T cells are associated with treatment response to neoadjuvant chemotherapy and prognosis in gastroesophageal adenocarcinoma.

Oncoimmunology·2025
Same journal

Brain-Derived Neurotrophic Factor, Sarcopenia and Digital Gait Characteristics in Older Adults: Insights Into the Brain-Muscle Axis.

Journal of cachexia, sarcopenia and muscle·2026
Same journal

Functional Outcomes and Quality of Life for Patients With Cachexia and Solid Tumour Cancers: Findings of a Systematic Literature Review.

Journal of cachexia, sarcopenia and muscle·2026
Same journal

Comment on 'Asian Reference Values for Handgrip Strength, Gait Speed, Five-Times-Sit-to-Stand Test, Muscle Mass and Calf Circumference' by Grgic et al.-The Authors' Reply.

Journal of cachexia, sarcopenia and muscle·2026
Same journal

Deletion of Tgf-β1 From CD206<sup>+</sup> M2 Macrophages Ameliorates Obesity-Induced Suppression of Myogenesis and AMPK Phosphorylation in Skeletal Muscle.

Journal of cachexia, sarcopenia and muscle·2026
Same journal

First Evaluation of Ultrafast Ultrasound Coupled With Phrenic Stimulation for Noninvasive Diagnosis of Diaphragm Dysfunction.

Journal of cachexia, sarcopenia and muscle·2026
Same journal

Comment on 'Asian Reference Values for Handgrip Strength, Gait Speed, Five-Times-Sit-to-Stand Test, Muscle Mass and Calf Circumference' by Grgic et al.

Journal of cachexia, sarcopenia and muscle·2026
See all related articles

Related Experiment Video

Updated: Jan 17, 2026

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
08:26

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Published on: March 24, 2023

1.4K

Sarcopenia in Colorectal Cancer Surgery-Minimally Invasive vs. Open.

Felix Merboth1,2,3,4, Miriam Müller-Oerlinghausen1, Heiner Nebelung5

  • 1Department of Visceral, Thoracic and Vascular Surgery, University Hospital and Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.

Journal of Cachexia, Sarcopenia and Muscle
|September 16, 2025
PubMed
Summary
This summary is machine-generated.

Minimally invasive surgery (MIS) does not prevent postoperative muscle loss in rectal cancer patients. Wound healing issues, not surgical approach, are key risk factors, and significant muscle loss correlates with poorer survival.

Keywords:
minimally invasive surgeryoncological outcomeopen surgeryrectal cancersarcopeniaskeletal muscle index

More Related Videos

Surgical Robot-Assisted Transanal Specimen Extraction Radical Sigmoidectomy Without an Auxiliary Abdominal Incision
07:22

Surgical Robot-Assisted Transanal Specimen Extraction Radical Sigmoidectomy Without an Auxiliary Abdominal Incision

Published on: June 13, 2025

680
Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
12:45

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer

Published on: February 12, 2022

6.4K

Related Experiment Videos

Last Updated: Jan 17, 2026

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
08:26

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

Published on: March 24, 2023

1.4K
Surgical Robot-Assisted Transanal Specimen Extraction Radical Sigmoidectomy Without an Auxiliary Abdominal Incision
07:22

Surgical Robot-Assisted Transanal Specimen Extraction Radical Sigmoidectomy Without an Auxiliary Abdominal Incision

Published on: June 13, 2025

680
Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
12:45

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer

Published on: February 12, 2022

6.4K

Area of Science:

  • Oncology
  • Surgical Innovation
  • Geriatrics

Background:

  • Sarcopenia, the loss of muscle mass and strength, affects up to 50% of cancer patients.
  • It worsens surgical complications and long-term cancer outcomes.
  • This study investigates if minimally invasive surgery (MIS) protects against sarcopenia post-rectal cancer resection.

Purpose of the Study:

  • To compare the impact of MIS versus open surgery on postoperative sarcopenia in rectal cancer patients.
  • To identify risk factors for muscle loss after rectal cancer surgery.
  • To analyze the relationship between sarcopenia and long-term oncological outcomes.

Main Methods:

  • Retrospective analysis of 145 patients undergoing open or MIS rectal resection (2013-2021).
  • Propensity score matching adjusted for confounding variables.
  • Skeletal Muscle Index (SMI) and Psoas Muscle Thickness per Height (PMTH) measured via CT scans pre- and post-surgery.

Main Results:

  • No significant difference in postoperative muscle loss between open and MIS groups over 3 years.
  • Wound healing disorders were the primary independent risk factor for significant muscle loss (>10% SMI loss).
  • Significant muscle loss (>10% SMI loss) was associated with poorer overall survival, disease-free survival, and increased recurrence/metastasis rates.

Conclusions:

  • MIS does not offer protection against postoperative sarcopenia in rectal cancer patients.
  • Postoperative muscle loss is a significant indicator of aggressive tumor behavior and poorer prognosis.
  • Interventions to minimize muscle loss, like nutritional support, are crucial for improving patient outcomes.