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Keloidal Dermatofibroma: A Rare Diagnostic Entity.

Vidya Viswanathan1, Anoushka Sharma2, Sushama Gurwale1

  • 1Professor, Department of Pathology, Dr D Y Patil Medical College, Hospital and Research Centre, Dr D Y Patil Vidyapeeth, Pune, Maharashtra, India.

The Journal of the Association of Physicians of India
|September 16, 2025
PubMed
Summary

This case study highlights a rare keloidal dermatofibroma on the neck, a benign fibrous histiocytoma variant. Early recognition and management are crucial for this atypical presentation.

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Area of Science:

  • Dermatology
  • Pathology
  • Oncology

Background:

  • Dermatofibroma, or benign fibrous histiocytoma, is a common skin tumor.
  • Neck presentation of dermatofibroma is associated with atypical features and aggressive behavior.
  • Keloidal dermatofibroma is an exceptionally rare subtype, accounting for ~1% of cases.

Purpose of the Study:

  • To report a case of keloidal dermatofibroma on the neck.
  • To discuss the clinicopathologic characteristics of this rare variant.
  • To review management strategies for neck keloidal dermatofibromas.

Main Methods:

  • Case report.
  • Histopathological examination of a nodular neck lesion.
  • Literature review on keloidal dermatofibroma management.

Main Results:

  • A nodular lesion on the neck was diagnosed as keloidal dermatofibroma.
  • Histopathology revealed keloid-like areas, spindle cells, and inflammatory infiltrate.
  • The case underscores the rarity and potential for misdiagnosis of this subtype.

Conclusions:

  • Keloidal dermatofibroma on the neck is a rare entity requiring careful diagnosis.
  • Atypical presentations necessitate thorough histopathological evaluation.
  • Optimal management strategies for this specific location warrant further investigation.