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Related Experiment Videos

Open lung biopsy in patients with diffuse pulmonary shadowing.

G E Venn, P H Kay, C J Midwood

    Thorax
    |December 1, 1985
    PubMed
    Summary

    Open lung biopsy provides a safe and reliable method for diagnosing diffuse pulmonary shadowing, achieving a high diagnostic yield with minimal complications. This procedure is crucial when radiological findings are non-specific, aiding in disease assessment.

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    Area of Science:

    • Pulmonology
    • Thoracic Surgery
    • Diagnostic Pathology

    Background:

    • Radiological appearances of diffuse pulmonary shadowing often lack specificity.
    • Histological examination is frequently required for accurate diagnosis and disease activity assessment.

    Purpose of the Study:

    • To evaluate the safety, efficacy, and diagnostic yield of open lung biopsy via a limited submammary incision.
    • To assess complications and outcomes in patients undergoing this procedure.

    Main Methods:

    • Open lung biopsy performed in 101 patients using a limited submammary incision between July 1979 and May 1983.
    • Histological examination of biopsy specimens to determine diagnostic specificity.
    • Analysis of patient data including prior investigations, corticosteroid use, complications, and mortality.

    Main Results:

    • Histological findings were specific enough for diagnosis in 92 patients.
    • Complications included respiratory tract infection (6 patients) and superficial wound infection (8 patients).
    • Four patients died, all with severe pre-existing lung disease; three underwent biopsy for undiagnosed progressive lung disease.

    Conclusions:

    • Open lung biopsy using a limited submammary incision is a safe and reliable procedure with a high diagnostic yield.
    • The approach offers good cosmetic results and minimal morbidity, making it a valuable diagnostic tool for diffuse pulmonary shadowing.

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