Alleviation of COVID-19 Parosmia with Stellate Ganglion Block: A Case Report

An estimated 23 million people in the United States are affected with Long COVID, formally called Postacute Sequelae SARS-CoV-2 infection (PASC). Disturbances of taste and smell are common symptoms. There is limited evidence for effective treatment.

A 68-year-old woman contracted COVID-19 in January 2021. She had worsening parosmia and dysgeusia, described as "rancid" smells with a variety of foods and objects. She underwent successful right stellate ganglion block in April 2022. Immediately after the procedure, she was able to comfortably eat food previously intolerable. Benefits persisted at 5- and 30-day follow-up.

An ever-expanding patient population and lack of treatment options emphasize the importance of continued research into the pathogenesis and treatment of PASC. A nascent body of evidence suggests stellate ganglion block may provide durable relief.