Related Experiment Video
Updated: Jun 30, 2026
Breathing-controlled Electrical Stimulation BreEStim for Management of Neuropathic Pain and Spasticity
Published on: January 10, 2013
Percutaneous Femoral Nerve Stimulation for Overactive Bladder: A Case Report
Navdeep Singh Manhas1, Standiford Helm2
1Department of Physical Medicine and Rehabilitation, Loma Linda University Health, Loma Linda, CA.
Background:
Peripheral nerve stimulation has been used to treat overactive bladder. A possible mechanism of action may be retrograde neuromodulation of the parasympathetic system via the sacral plexus. If the retrograde neuromodulation theory is correct, then stimulation of any nerve not arising from the sacral plexus should not improve overactive bladder symptoms.
Case Report:
We present a case of femoral nerve stimulation for neuropathic pain. While the stimulation did not relieve the neuropathic pain, it did successfully treat our patient's hyperactive bladder.
Conclusions:
The femoral nerve arises in part from L2, the lowest level of the sympathetic system. The sympathetic system is involved with relaxation of the bladder. This report shows that nerves not arising from the sacral plexus can relieve overactive bladder symptomology. A refinement of the retrograde neuromodulation theory may be called for, with the inclusion of sympathetic neuromodulation as an alternative means to treat hyperactive bladder.
