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Percutaneous Femoral Nerve Stimulation for Overactive Bladder: A Case Report
Navdeep Singh Manhas1, Standiford Helm2
1Department of Physical Medicine and Rehabilitation, Loma Linda University Health, Loma Linda, CA.
Pain Medicine Case Reports
|September 16, 2025
Summary
Femoral nerve stimulation, not originating from the sacral plexus, successfully treated overactive bladder (OAB) in a case study. This challenges existing theories and suggests sympathetic neuromodulation may offer new OAB treatment options.
Area of Science:
- Neurology
- Urology
- Pain Management
Background:
- Peripheral nerve stimulation is a known treatment for overactive bladder (OAB).
- The proposed mechanism involves retrograde neuromodulation of the parasympathetic system via the sacral plexus.
- Current theory suggests only sacral plexus nerves can modulate OAB symptoms.

