Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Catalysis02:50

Catalysis

30.1K
The presence of a catalyst affects the rate of a chemical reaction. A catalyst is a substance that can increase the reaction rate without being consumed during the process. A basic comprehension of a catalysts’ role during chemical reactions can be understood from the concept of reaction mechanisms and energy diagrams.
30.1K
Measuring Reaction Rates03:09

Measuring Reaction Rates

28.6K
Polarimetry finds application in chemical kinetics to measure the concentration and reaction kinetics of optically active substances during a chemical reaction. Optically active substances have the capability of rotating the plane of polarization of linearly polarized light passing through them—a feature called optical rotation. Optical activity is attributed to the molecular structure of substances. Normal monochromatic light is unpolarized and possesses oscillations of the electrical...
28.6K
Introduction to Mechanisms of Enzyme Catalysis01:13

Introduction to Mechanisms of Enzyme Catalysis

10.5K
For many years, scientists thought that enzyme-substrate binding took place in a simple "lock-and-key" fashion. This model stated that the enzyme and substrate fit together perfectly in one instantaneous step. However, current research supports a more refined view scientists call induced fit. The induced-fit model expands upon the lock-and-key model by describing a more dynamic interaction between enzyme and substrate. As the enzyme and substrate come together, their interaction causes...
10.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Catalytic synthesis of saturated azacycles using transborylation.

Organic & biomolecular chemistry·2026
Same author

Three Component Thio- and Carboboration of Alkynes: A Modular Route to Functionalised Bicyclic Boronates.

Angewandte Chemie (International ed. in English)·2026
Same author

Stereoselective, borane-catalysed synthesis of <i>syn</i>-β-hydroxyketones from α,β-unsaturated ketones.

Chemical science·2026
Same author

Molecular-level insight into the multiple mechanistic pathways in iron-catalysed alkene dimerisation.

Chemical science·2025
Same author

Ligand non-innocence and an unusual σ-bond metathesis step enables catalytic borylation using 9-borabicyclo-[3.3.1]-nonane.

Chemical science·2025
Same author

Multifaceted Hidden Catalysis Revealed by Mechanistic Analysis of FeBr<sub>3</sub>-Catalysed Arene Borylation.

Angewandte Chemie (International ed. in English)·2024

Related Experiment Video

Updated: Jan 17, 2026

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

751

Colorimetric indication of hidden catalysis.

Julie Macleod1, Stephen P Thomas2

  • 1EaStCHEM School of Chemistry, The University of Edinburgh, Edinburgh, UK.

Nature Chemistry
|September 16, 2025
PubMed
Summary

Chemists can now rapidly detect hidden borane catalysis using a simple colorimetric indicator. This visual method avoids lengthy analyses, accelerating chemical synthesis and improving mechanistic understanding.

More Related Videos

Visualization of Mitochondrial Respiratory Function using Cytochrome C Oxidase / Succinate Dehydrogenase COX/SDH Double-labeling Histochemistry
06:53

Visualization of Mitochondrial Respiratory Function using Cytochrome C Oxidase / Succinate Dehydrogenase COX/SDH Double-labeling Histochemistry

Published on: November 23, 2011

37.6K
Quantifying the Modulation of Elastase Enzyme Activity Through Colorimetric Analysis
04:30

Quantifying the Modulation of Elastase Enzyme Activity Through Colorimetric Analysis

Published on: January 17, 2025

2.0K

Related Experiment Videos

Last Updated: Jan 17, 2026

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

751
Visualization of Mitochondrial Respiratory Function using Cytochrome C Oxidase / Succinate Dehydrogenase COX/SDH Double-labeling Histochemistry
06:53

Visualization of Mitochondrial Respiratory Function using Cytochrome C Oxidase / Succinate Dehydrogenase COX/SDH Double-labeling Histochemistry

Published on: November 23, 2011

37.6K
Quantifying the Modulation of Elastase Enzyme Activity Through Colorimetric Analysis
04:30

Quantifying the Modulation of Elastase Enzyme Activity Through Colorimetric Analysis

Published on: January 17, 2025

2.0K

Area of Science:

  • Organic Chemistry
  • Catalysis
  • Chemical Synthesis

Background:

  • Hidden catalysis, where unintended species influence reactions, complicates chemical synthesis.
  • Existing methods for detecting hidden catalysis are time-consuming and labor-intensive.
  • Hidden borane catalysis is a significant challenge in reaction development.

Purpose of the Study:

  • To develop a rapid, visual method for detecting hidden borane catalysis.
  • To provide a practical tool for chemists to identify and mitigate hidden catalytic effects.
  • To accelerate the discovery and optimization of chemical reactions.

Main Methods:

  • Development of a novel colorimetric indicator.
  • Application of the indicator for in situ reaction monitoring.
  • Utilizing the indicator for reagent quality control and test strip analysis.

Main Results:

  • The colorimetric indicator provides rapid, visual detection of hidden borane catalysis.
  • The test was successfully applied in various settings, including reaction sampling and quality control.
  • The method eliminates the need for complex mechanistic studies.

Conclusions:

  • The colorimetric indicator offers a transformative solution for identifying hidden borane catalysis.
  • This tool empowers chemists to accelerate reaction optimization and discovery.
  • Improved mechanistic understanding through rapid detection will advance chemical synthesis.